hrp0094fc1.4 | Adrenal | ESPE2021

Acute Illness and Death in Children with Adrenal Insufficiency

Worth Chris , Vyas Avni , Banerjee Indraneel , Lin John , Jones Julie , Stokes Helen , Komlosy Nicci , Ball Steve , Clayton Peter ,

Background: Adrenal Insufficiency (AI) is a heterogeneous diagnosis comprising multiple central and peripheral causes. The unifying feature is the requirement for glucocorticoid replacement and subsequent risk of life-threatening Adrenal Crisis (AC) and Adrenal Death (AD). Very few studies have investigated rates of AD in children. Multiple studies have reported symptoms of children with AC as interpreted by medical staff but no studies have looked at parental...